❞ كتاب The BlooddBrain Barrier and Drug Delivery to the CNS ❝  ⏤ Michael Bradbury, David Begley, Jorg Kreuter

❞ كتاب The BlooddBrain Barrier and Drug Delivery to the CNS ❝ ⏤ Michael Bradbury, David Begley, Jorg Kreuter

نبذه عن الكتاب:

Among the factors that influence uptake and distribution of a drug into a tissue
or organ outside the central nervous system (CNS) are blood flow, binding to
proteins in blood plasma, clearance from blood, and metabolism. Since capillaries in general have numerous water-filled channels across their walls which
allow ready escape of solutes up to the size of small proteins into interstitial
fluid, capillary permeability is not normally a factor in limiting drug uptake.
The contrary is true for brain and spinal cord. The blood–brain barrier (BBB)
is frequently a rate-limiting factor in determining permeation of a drug into
brain and is also an element in influencing steady state distribution. It is commonplace for pharmacologists and pharmaceutical chemists to make predictions concerning the pharmacological activity of a potential drug from its molecular structure. Those administering drugs active on cells of the CNS are
generally concerned to raise and maintain an optimum concentration of the
agent in the cerebral interstitial fluid where it is in contact with receptors. It
would be most helpful to be able to predict both permeability at the BBB and
steady state distribution of a potential neuropharmacological agent from its
molecular structure.
Michael Bradbury, David Begley, Jorg Kreuter - ❰ له مجموعة من الإنجازات والمؤلفات أبرزها ❞ The BlooddBrain Barrier and Drug Delivery to the CNS ❝ ❱
من Biology Books علم الأحياء - مكتبة الكتب العلمية.

نبذة عن الكتاب:
The BlooddBrain Barrier and Drug Delivery to the CNS

2000م - 1445هـ
نبذه عن الكتاب:

Among the factors that influence uptake and distribution of a drug into a tissue
or organ outside the central nervous system (CNS) are blood flow, binding to
proteins in blood plasma, clearance from blood, and metabolism. Since capillaries in general have numerous water-filled channels across their walls which
allow ready escape of solutes up to the size of small proteins into interstitial
fluid, capillary permeability is not normally a factor in limiting drug uptake.
The contrary is true for brain and spinal cord. The blood–brain barrier (BBB)
is frequently a rate-limiting factor in determining permeation of a drug into
brain and is also an element in influencing steady state distribution. It is commonplace for pharmacologists and pharmaceutical chemists to make predictions concerning the pharmacological activity of a potential drug from its molecular structure. Those administering drugs active on cells of the CNS are
generally concerned to raise and maintain an optimum concentration of the
agent in the cerebral interstitial fluid where it is in contact with receptors. It
would be most helpful to be able to predict both permeability at the BBB and
steady state distribution of a potential neuropharmacological agent from its
molecular structure. .
المزيد..

تعليقات القرّاء:

Biologically

Biology is a natural science that is concerned with the study of life, its various forms and its function, how these organisms interact with each other and with the surrounding environment. The word biology in Greek is made up of two words: bio (βίος) meaning life. And loggia (-λογία) means science or study. Biology: the similarity of vegetation and animal cover on the edges of the African and American states, and the existence of the same fossil.


Branches of biology
Biology is an ancient science thousands of years old and modern biology began in the nineteenth century. This science has multiple branches. Among them are:

Anatomy
Botany
Biochemia
Biogeography
Biofisia
Cytology or cell science
Ecology or environmental science

 

 

نبذه عن الكتاب:

Among the factors that influence uptake and distribution of a drug into a tissue
or organ outside the central nervous system (CNS) are blood flow, binding to
proteins in blood plasma, clearance from blood, and metabolism. Since capillaries in general have numerous water-filled channels across their walls which
allow ready escape of solutes up to the size of small proteins into interstitial
fluid, capillary permeability is not normally a factor in limiting drug uptake.
The contrary is true for brain and spinal cord. The blood–brain barrier (BBB)
is frequently a rate-limiting factor in determining permeation of a drug into
brain and is also an element in influencing steady state distribution. It is commonplace for pharmacologists and pharmaceutical chemists to make predictions concerning the pharmacological activity of a potential drug from its molecular structure. Those administering drugs active on cells of the CNS are
generally concerned to raise and maintain an optimum concentration of the
agent in the cerebral interstitial fluid where it is in contact with receptors. It
would be most helpful to be able to predict both permeability at the BBB and
steady state distribution of a potential neuropharmacological agent from its
molecular structure.


Biology
Human biology
Who is the founder of biology?
The importance of biology
Areas of work in the field of biology
Theories of biology
Research on biology for the first grade of secondary school
Human biology

 



سنة النشر : 2000م / 1421هـ .
حجم الكتاب عند التحميل : 2.15 .
نوع الكتاب : pdf.
عداد القراءة: عدد قراءة The BlooddBrain Barrier and Drug Delivery to the CNS

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المؤلف:
Michael Bradbury, David Begley, Jorg Kreuter -

كتب Michael Bradbury, David Begley, Jorg Kreuter ❰ له مجموعة من الإنجازات والمؤلفات أبرزها ❞ The BlooddBrain Barrier and Drug Delivery to the CNS ❝ ❱. المزيد..

كتب Michael Bradbury, David Begley, Jorg Kreuter